No cure for HIV/AIDS yet – NACA refutes Ezeibe’s claims

The National Agency for the Control of Aids (NACA) has refuted the claim by Maduike Ezeibe, a professor of veterinary medicine and clinical virology at the Michael Okpara University of Agriculture, that he has finally discovered a new drug for the cure of HIV/AIDS.

The professor claimed the drug, which was produced with “Aluminium Magnesium Silicate” has allegedly cured 10 persons living with HIV.

However, a rejoinder signed by Dr Sani Aliyu Director-General, NACA and Dr Chikwe Ihekweazu, CEO Nigeria Centre for Disease Control (NCDC), said the claim for a HIV/AIDS cure was not new.
“It is also not new to find a scientist using ambiguous scientific methods and practices to buttress this claim, and to find obscure journals increasingly prepared to publish these claims. Following the discrediting of the claims of Dr Abalaka in the late 90’s, we had also hoped that the Nigerian press would thoroughly investigate these “AIDS cure”, claims before going to press, given the huge impact that these could have on patients’ lives.
“Without controls, you can neither have randomisation nor blinding, two other critical factors in studying the effects of new medicines”, the statement read.
NACA added that the primary outcome measured in claim cure study was based on plasma viral load levels, which are known to fluctuate in patients, even in the absence of any intervention.

“It is also worth noting that virological suppression (viral load less than 50 copies/ml) was not achieved in 6 of 8 patients. There appeared to be no medical doctor involved in the execution of this study and there was no evidence on where or how the patients were treated or monitored during this study, their clinical and treatment status at the beginning or at the end of it.
“It is important to note that clinical trials are conducted in a series phases – each phase is designed to answer a separate research question. These include; 1.) Phase I: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety 2.) Phase II: The drug or treatment is given to a larger group of people to see if it is effective 3.) Phase III: The drug or treatment is given to large groups of people to confirm its effectiveness, comparing it to commonly used treatments, and Phase IV: Studies are done to gather information on the drug’s effect in various populations and any side effects associated with long-term use. The authors of this study did not state what phase their study was and the results of previous phases, if these were done.
“There are long established, tried and tested routes for the discovery, development and validation of modern medicines before they can be registered and used for treatment in humans and animals. We call on all academics to follow legal and scientifically acceptable methods in conducting their research and to avoid making premature claims that are capable of derailing the huge progress made in the last two decades on the war against HIV/AIDS. Millions of lives have been saved as a result of modern antiretroviral treatment and people living with HIV can now look forward to a normal healthy future.
“We continue to support the hard and diligent work being done by scientists in our Universities and research institutions around the country. We are always ready to partner with our scientists on all aspects of HIV research provided this is in line with international best practice.

“We call on all patients living with HIV that are currently taking their medications to continue to do so and to see their doctors if they have any concern. The NACA helpline (6222) is available on working days from 8am-8pm for members of the public seeking more information on HIV disease”, it said.