Contrary
to widely published reports that the conventional vaccine for
tuberculosis (TB) offers protection against the novel coronavirus, the
World Health Organisation (WHO), yesterday, dismissed the claim.
The apex United Nations health body said there was no evidence that
the Bacille Calmette-Guérin vaccine (BCG) protects people against the
virus.
The global agency stated that clinical trials relating to the issue
were underway, adding that their outcome would be evaluated in due
course.
It said: “In the absence of evidence, WHO does not recommend BCG
vaccination for the prevention of COVID-19. WHO continues to recommend
neonatal BCG vaccination in countries or settings with a high incidence
of tuberculosis.
“There is experimental evidence from both animal and human studies
that the BCG vaccine has non-specific effects on the immune system.
These effects have not been well characterised and their clinical
relevance is unknown.
“On April 11, 2020, WHO updated its ongoing evidence review of the
major scientific databases and clinical trial repositories, using
English, French and Chinese search terms for COVID-19, SARS-CoV-2 and
BCG.
“The review yielded three preprints (manuscripts posted online before
peer-review) in which the authors compared the incidence of COVID-19
cases in countries where the BCG vaccine is used with countries where it
is not used and observed that countries that routinely used the vaccine
in neonates had less reported cases of COVID-19 to date. Such
ecological studies are prone to significant bias from many confounders,
including differences in national demographics and disease burden,
testing rates for COVID-19 virus infections, and the stage of the
pandemic in each country.
“The review also yielded two registered protocols for clinical
trials, both of which aim to study the effects of BCG vaccination given
to healthcare workers directly involved in the care of patients with
COVID-19.
“BCG vaccination prevents severe forms of tuberculosis in children
and diversion of local supplies may result in neonates not being
vaccinated, resulting in an increase of disease and deaths from
tuberculosis. In the absence of evidence, WHO does not recommend BCG
vaccination for the prevention of COVID-19. WHO continues to recommend
neonatal BCG vaccination in countries or settings with a high incidence
of tuberculosis.”
Meanwhile, the first United Nations “Solidarity Flight” left Addis
Ababa, Ethiopia yesterday to deliver vital medical supplies to all
African nations for the containment of the COVID-19 scourge.
WHO said its cargo was transported by the United Nations World Food
Programme (WFP) and it included face shields; gloves; goggles; gowns;
masks, aprons, thermometers as well as ventilators.
The agency added that the consignment also had supplies from Prime Minister Abiy Ahmed and Jack Ma Foundation Initiative.
Director-General of WHO, Dr. Tedros Adhanom Ghebreyesus; the Regional
Director for Africa, Dr. Matshidiso Moeti, and WFP’s Executive
Director, David Beasley, made the confirmations.
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